1. Which of the following medications is NOT considered an imidazoline derivative? ?
Oxymetazoline (Afrin)
Tetrahydrozoline (Visine)
Tizanidine (Zanaflex)
Phenylephrine (Sinex)

2. The imidazoline agents reviewed mainly exhibit effects on this receptor ?
Alpha
Beta
Mu
Nicotinic
Serotonergic

3. Clonidine was initially developed to treat ADHD in children. ?
True
False

4. A clinical effect NOT commonly seen with imidazoline ingestion is: ?
Bradycardia
Miosis
Lethargy
Vivid hallucinations
Hypotension

5. Your nurse sister calls you regarding a possible Visine ingestion by your nephew. You can tell her that the hospital will be able to confirm the ingestion on a comprehensive tox screen: ?
True
False

6. Treatment of imidazoline toxicity may include the following EXCEPT: ?
Flumazenil, a known reversal agent
Dopamine, a vasopressor
Gastrointestinal decontamination
Supportive care and observation

7. The upward trend of reported clonidine exposures in children is most likely due to: ?
Parents not watching their kids
The poison control center advocating phone calls
Grandma’s new found home remedy
More doctors prescribing the medicine to treat children for ADHD

8. Most imidazoline exposures result in: ?
Long-lasting sequelae
Death
Resolution of symptoms within 24 hours
Seizures

9. The following symptom should NOT be expected when a school boy puts imidazoline derived eye drops in his friend’s drink: ?
Diarrhea
Hypotension
Fatigue
Dizziness

10. Emergency department staff should be prepared for all of the following with an imidazoline toxicity EXCEPT: ?
Possible tracheal intubation
IV fluid challenge for hypotension
Possible administration of activated charcoal
Hyperthermia
Possible administration of Atropine

11. Naloxone’s place in therapy for imidazoline toxicity is regarded as ?
The drug of choice for reversal of symptoms
May be effective but this is controversial
Likely to cause CNS depression
Likely to cause withdrawal seizures